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Treatment Options
 

 The treatment information on this page and the search icons that follow are not meant to replace the advice and treatment of a qualified doctor of oncology. We do hope to provide you with some general information on treatment options as well as provide you with the names of oncologists and cancer treatment centers throughout the Country. If you have been diagnosed with leukemia or another form of cancer you should seek immediate help from an oncology specialist, a hematologist, and a specialist in radiation oncology.  These professionals are trained in diseases of the blood and specialize in the treatment of cancer. It never hurts to seek second opinions when you are diagnosed with a potentially life ending disease.

People who suffer from Leukemia are generally treated with one or more of the following modalities; chemotherapy, radiation therapy, bone marrow or stem cell transplants, and monoclonal antibodies.

We believe it is critical for you to consult with the best specialist you can find. Again, do not be afraid to seek a second opinion, or at the very least consult a team of Doctors who specialize in the treatment of Leukemia. Just like lawyers, two Doctors in the same field of medicine may have very different opinions regarding your treatment. If you are not the type of person who likes to ask questions or are intimidated by Doctors, you may want to consider appointing someone to act as your advocate. In our experience, often your spouse is your best advocate. Again, just like choosing a lawyer, do not be afraid to ask questions regarding a Doctors experience in these matters, does the Doctor truly specialize in this field, has the Doctor successfully treated patients in your condition before. Above all, remember you may be in the fight of and for your life; you need the best and most up to date information available, you need to make the most informed decisions possible and you need the care and treatment of an experienced, trained and caring professional.



Chemotherapy

 Just about everybody has heard the term Chemotherapy. Most people know that it is a treatment for cancer. For many of us, our understanding of Chemotherapy ends there simply because like most unpleasant things we would rather not know or think about it unless we have to. Cancer is no joke, you hear a lot of people refer to it as the C-word because they don’t like to even say the word. We all hope and pray that if we live a healthy life , we will live a long time, watch our kids and grandkids  grow and prosper and when our time comes we will go quick and hopefully while we are sleeping.. Unfortunately, you or a loved one may have done all the right things only to be unwittingly poisoned by Benzene and now you are in the fight of your life. Chemotherapy is the use of chemicals that are put into the body as therapy for the cancer. Cancer cells are cells that grow rapidly in the body, chemotherapy drugs are formulated to target rapidly growing cells like cancer cells and kill them. An early detection of cancer in the body usually means your chances of survival increase because the cancer cells have had less time to grow and spread throughout the body. Chemotherapy is often the first line of defense in the fight against cancer. Chemotherapy drugs are very strong because they are designed to kill rapidly growing vibrant cells. Chemotherapy drugs as a general rule do not discriminate among rapidly growing cells so they can have side effects such as hair loss, nausea, fatigue, loss of weight from loss of appetite, a weak immune system that can make you susceptible to other ailments and other side effects.  Side effects from chemotherapy are much better controlled today than they were in the past.  Still, some times you will hear people say ,” If I ever got the big C-word I would never go for chemo.” They say that because a lot of us have known somebody who underwent chemotherapy, suffered  all the side effects and succumbed  to the cancer anyway. I suppose that is one way of looking at things and talk like that is easier said then done.  The truth is, there are many, many cases of people who owe their lives to Chemotherapy. Lance Armstrong, the international biking super star comes immediately to mind. I have had clients who have beaten the worst forms of cancer and I have had relatives who have beaten cancer and lived cancer-free for years. You need to make a decision in conjunction with your doctors and family to pursue the treatment option that is best for you based on all the information that is available. Below are some excellent links to non-lawyer sites that have extensive information on chemotherapy,  I have already done the search for you, all you need to do is “click” on the the hyperlink .

 

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http://www.leukemia-lymphoma.org/hm_lls

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http://www.nlm.nih.gov/medlineplus/cancerchemotherapy.html

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http://www.cancer.gov/cancertopics/chemotherapy-and-you

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http://www.chemocare.com

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http://topics.nytimes.com/top/news/health/diseasesconditionsandhealthtopics/chemotherapy/index.html?inline=nyt-classifier

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http://www.cancerhelp.org.uk/default.asp?page=165

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http://www.oncolink.org/treatment/article.cfm?c=2&s=9&id=55

 

Radiation Therapy

 
Radiation therapy is  the treatment of cancer using penetrating beams of high or streams of particles called radiation. Radiation is given in high doses to kill cancer cells or to stop these rapidly growing cells from continuing to grow and divide. Although radiation can also harm  heathy cells most will recover while cancer cells generally will not. Radiation therapy is generally targeted  to a specific area of the body or directly at a tumor.  In this way it is different from chemotherapy which is a systemic treatment because chemotherapy reaches all parts of the body. Often radiation therapy in used in conjunction with chemotherapy. When added to a regime of chemotherapy, radiation therapy is an adjuvant therapy. Radiation therapy can also be used on the entire body  in a leukemia patient before a stem cell or bone marrow transplant. Side effects of radiation therapy  vary from person to person, some patients suffer serious side effects whileothers may expierience little or none. Side effects to radiation may be acute or chronic. Acute side effects are those that occur soon after the radiation therapy but are gone after a few weeks of discontuance of the radiation therapy while chronic side effects can last years.  Generally the side effects of radiation therapy are fatigue, loss of appetite,skin rashes, dry, sensitive skin, and emotional difficulties.. Fatigue is the most common side effect .Doctors are unsure if it is because of the cancer itself, the radiation or a little of both.  Coping with possible side effects is yet another area where it is important to surrond yourself with the best medical and spiritual care available. Below are some excellent non-lawyer links to sites with extensive information about radiation therapy. I have already done the search for you, all you need to do is "click" on the hyperlink. 

 


Bone Marrow Transplant and  Stem Cell transplant


 Bone marrow transplatation was first successfully used in 1968.It has been used to treat and cure many diseases thought to be incurable. Bone marrow transplantation is a regocnized medical procedure for Leukemia,aplastic anemia, various lymphomas and tumors  found in breast and ovarian cancer. Bone marrow is the tissue found on the inside of bones. Some bone marrow in the human body contains very beneficial cells like white blood cells, which fight infections and red blood cells which carry oxygen .While a reletively new procedure, BMT is becoming somewhat common with over 7,500 procedures in the U.S ayear. In leukemia patients the stem cells in the bone marrow produce excessive defective cells which accumulate in the blood stream and interfer with the production of normal cells. In order to destroy the defective cells large doses of chemotherapy and/or and radiation are used which has the side effect of killing the normal cells as well. A BMT allows your Doctor to aggressively treat the cancer because the damaged bone marrow is going to be replaced.  

 

An "allogeneic"BMT is when the bone marrow is harvested from a donor, usually a blood relative like a brother or sister. Like any transplant ther is a risk of rejection so  in a allogeneic BMT it is critical to get as close of a genetic match as possible. Statisically, there is a 35% chance that a sibling will be a perfect match.

 

In  some situations , it may be possible to do an BMT using the patients own bone marrow cells.  The cells are harvested while  the patient is in remission or if the disease being treated  does not involve the bone marrow. Transplants using the patients own bone marrow are called "autologous" transplants.

 

 Of interest is that the procedure for harvesting the bone marrow is more evasive than the transplatation itself. The procedure for the harvesting takes place in the hospital operating room and is the same whether the patient or a donor provides the marrow. The marrow is harvested from the "iliac crest",  the rear portion of the hip bone by inserting a needle into the bone and drawing out the marrow. This procedure is done with the patient under anesthesia. About one or two quarts are  harvested. The amount harvested depends on the donors size and the concentation of marrow cells. In the case of a donor the bone marrow may be treated to reduce the risk of rejection but is then  taken to be transplated into the patient directly. If it is the patient own marrow which is harvested it i may be purged or cleaned of any residual cancer cells and then frozen to be re-introduced to the patient at a later date.se tia cavityInterestlyhas not in Usually the patient’s blood stem cells are collected and frozen, and then reintroduced into the patient after he/she has received intensive chemotherapy and/or radiation therapy. 

 

The transplation of the bone marrow is  done intravenously as any blood product would be.It is not a surgical procedure so it is done in the patients room and not the operating room. The preperation for the transplant can be trying as the dosage of chemotherapy and/or radiation  administered to "condition" the patient for the transplant are much greater than for someone who has the same disease but not undergoing BMT.

 

The first month following a BMT is the most tense. The "conditioning" period has had the desired effect of destroying the bone marrow cells so the new cells can  engraft and produce normal cells, but it has also left the patients' immune  system in tatters.It takes about a month for the bone marrow to produce normal cells so until then a patient is extremely susceptible to ifections and bleeding. Multiple blood transfusions and antibiotics will be given during this period.

 

Should youundergo a BMT be prepared to find and lean on all the support you can get. Times like these remind us all  of the importance of family.A BMT is an emotionally trying procedure because the side effects from the chemo and/or radiation therapy at such  high doses will cause a patient to feel very ill and sick for several weeks.

 

A BMT is no  a difficult procedure to undergo but if near certain death is the alternative it is worthwhile.

 

Below are more hyperlinks to non-lawyer sites with excellent information on BMT. Just "click" and go

 

 

 

Stem Cell transplant is very similar to bone marrow transplant, the procedures and reasons behind them being much the same.

 

Below are more hyperlinks to non-lawyer sites with excellent information on Stem cell transplantation. Just"click" and go.

 


Immunotherapy or Monoclonal Antibodies

Monoclonal antibodies are  proteins that are produced in the laboratory which are put ito a patients body. These antibodies can be made to interact with the cancer cells in Luekemia patients  such that they attach themselves to the tumor cell causing it to be destroyed.  These antibodies are sometimes called"naked antibodies" because they do not carry a radioactive agent or toxin to kill the tumor cell they attach to. In May 200 the FDA approved the drug Mylotarg(registerd tade name) for the treatment of Acute Myelogenous leukemia. This drug is indicated for older patients who have relapsed.eeused to assist the body’s immune system in getting rid of the disease. Once the monoclonal antibodies are put into the patient’s body, they seek out and bind themselves to the leukemia cells. Then the immune system responds by destroying the antibodies and the cancer cells simultaneously. However, it is important to keep in mind that monoclonal antibodies are a recent development in leukemia treatment, thus the long-term effectiveness is still being investigated.

Below are more hyperlinks to non-lawyer links with excellent information on Immunotherapy

 

 

 

Additional Links to information

 

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ATSDR - CSEM - Benzene Toxicity:

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Role of Nitric Oxide in Hematosuppression and Benzene-induced Toxicity

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Entrez PubMed
 

 

If you have any questions regarding treatment or your legal rights, please contact us through our Case Evaluation Form or contact us at:

  (800) 569-2325 • (866) Tex-Laws

 

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